ANGIOFIBROMA NASOFARING JUVENILE PDF

Jinak tetapi merupakan tumor pembuluh darah lokal yang agresif dari anak atau remaja laki-laki, pernah juga dilaporkan pada perempuan tetapi sangat jarang. Tetapi istilah juvenile ini kurang tepat karena neoplasma ini terdapat juga pada pasien yang lebih tua. Dilaporkan insidennya antara 1 : 5. Di RSUP.

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Nikojar Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ]. Arch Pathol Lab Med ; The color depends on the vascular component and may vary from pale white in less vascular lesions to a pink and wine colored mass in highly vascularized ones.

Steroid hormone receptor expression in nasopharyngeal angiofibromas. Intraoral swelling was diffuse, obliterating the vestibule and extending from the lateral incisor anteriorly till the pharynx posteriorly [ Figure 1 ]. Bony erosion of nasofarjng nasal cavity, hard palate and pterygoid plates is also common.

Juvenile nasopharyngeal angiofibroma Edit article Share article View revision history. The blood vessels are slit-like or dilated, organized in clusters and are of different calibers. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Genetic evidence for an androgen-dependent tumor? Pathology Outlines — Nasopharyngeal angiofibroma The presentation is typically with obstructive symptoms, epistaxisand chronic otomastoiditis due to obstruction of the Eustachian tube.

Mesothelioma Malignant solitary fibrous tumor. The excised gross specimen was soft to firm in consistency, white to yellow with darker juvwnile areas. Nasopharyngeal angiofibroma also called juvenile nasopharyngeal angiofibroma [1] [2] is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity. Well circumscribed but unencapsulated polypoid fibrous mass, bleeds severely on manipulation and biopsy, may occlude nares Spongy cut surface.

It is, as the name suggests, very vascular and a biopsy can sometimes be fatal. Genetic alterations in juvenile nasopharyngeal angiofibromas. Abstract Juvenile nasopharyngeal angiofibroma JNA is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. The exact site of origin is contentious as these masses usually present when they have reached considerable size. Read it at Google Books — Find it at Amazon. Impaired Eustachian tube function, facial deformity, proptosis and changes in visual acuity may be seen.

Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI. Thank you for updating your details. Juvenile nasopharyngeal angiofibroma JNA is a benign neoplasm of the nasopharynx. Consistent expression of estrogen receptor beta. The infratemporal fossa approach for nasopharyngeal tumors.

Juvenile nasopharyngeal angiofibroma Radiology Reference Article Provisional diagnosis of nasopharyngeal angiofibroma, soft tissue tumor, nasopharyngeal polyp or vascular tumor was made. CT images show a heterodense mass that is centered in the sphenopalatine foramen. Early diagnosis and treatment are required for a good prognosis in JNA. CT is particularly useful at delineating bony changes.

Open in a separate window. Relative distribution of the tumours of ear, nose and throat in the paediatric patients. Numerical sex chromosome aberrations in juvenile angiofibromas: Computed tomography CT scan showed the presence of a soft tissue mass nasofarnig the maxillary sinus, nasal cavity, and nasopharynx. Avid enhancement is noted on contrast-enhanced CT. However, since a vast majority of the cases do occur between 14 and 25 years of age, this term is retained.

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Juvenile nasopharyngeal angiofibroma

E-mail: moc. This article has been cited by other articles in PMC. Abstract Juvenile nasopharyngeal angiofibroma JNA is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium. Clinically, however, it is obscure with painless, progressive unilateral nasal obstruction being the common presenting symptom with or without epistaxis and rhinorrhea. Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy and by using specialized imaging techniques such as arteriography, computer tomography and magnetic resonance imaging.

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Angiofibroma nasofaríngeo juvenil

They account for only 0. Clinical presentation The presentation is typical with obstructive symptoms, epistaxis , and chronic otomastoiditis due to obstruction of the Eustachian tube. Patients may present with life-threatening epistaxis. On examination, it may be seen as a pale reddish-blue mass. It is, as the name suggests, very vascular and a biopsy can sometimes be fatal.

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Nasopharyngeal angiofibroma

The excised gross specimen was soft to firm in consistency, white to yellow with darker vascular areas. Markers of vascular differentiation, proliferation and tissue remodeling in juvenile nasopharyngeal angiofibromas. Thank you for updating your details. Case 2 Case 2. See staging of juvenile nasopharyngeal angiofibromas.

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